Laser Science and Technology
Tuqa Sabah; kareem H. Jawad; Nebras Essam
Abstract
Along with its uses in a wide range of sectors, NP toxicity research was one of the fastest-growing areas of research, so the growing commercial applications brought aluminum oxide nanoparticles under the purview of toxicologists. This study shows the toxicity of Aluminum oxide Nanoparticles on blood ...
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Along with its uses in a wide range of sectors, NP toxicity research was one of the fastest-growing areas of research, so the growing commercial applications brought aluminum oxide nanoparticles under the purview of toxicologists. This study shows the toxicity of Aluminum oxide Nanoparticles on blood components prepared using the pulsed laser ablation (PLA) Nd: YAG laser method. We confirmed the synthesis of aluminum Oxide nanoparticles by measuring color absorbance, UV-vis, scanning electron microscope techniques (SEM), and FTIR as characterization of Aluminum oxide Nanoparticles. The complete blood count (CBC) was used in the study of the toxicity effect of these nanoparticles on human blood parameters (in vitro). The results of hematology parameter platelet (PLT); hemoglobin (HGB–Hb); red blood cell (RBCs); white blood cell (WBCs); Count type white blood cells) are compared with the control groups, our results show no significant differences in levels of platelet (PLT); hemoglobin (HGB –Hb); red blood cell (RBCs); white blood cell (WBCs); Count type white blood cells) between the test groups when compared with control groups. This result that there indicates no toxic effect of Aluminum oxide nanoparticles in the hematology parameter (in vitro). This work is done for the first time to investigate the non-toxicity effect of these Al2O3 NPs on human blood parameters.
Nanotechnology
Anwar Sabri Jawad; Qasim N. Thewaini; Sharafaldin Al-Musawi
Abstract
Aluminum oxide, often known as Al2O3, is a chemical compound of aluminum and oxygen with the formula Al2O3. It's the most common of many aluminum oxides, known as aluminum (III) oxide. The study investigates the cytotoxicity and antibacterial effects of Aluminum oxide nanoparticles (Al2O3-NPs) in different ...
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Aluminum oxide, often known as Al2O3, is a chemical compound of aluminum and oxygen with the formula Al2O3. It's the most common of many aluminum oxides, known as aluminum (III) oxide. The study investigates the cytotoxicity and antibacterial effects of Aluminum oxide nanoparticles (Al2O3-NPs) in different cells and bacteria. Different characterization methods such as dynamic light scattering (DLS), field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR) have been used to evaluate morphologies and physicochemical properties of Al2O3-NPs. MTT technique is used for determining NPs cytotoxicity. The size distribution of Al2O3-NPs was 68 ± 12 nm in diameter, while the zeta potential was (-36 ± 10 mV). There is no toxicity by using the MTT assay, as well as showed antibacterial activity was formed at 200 µg/mL, while the higher antibacterial activity was occurring at (18 ± 0.2) and (17 ± 0.1) for Proteus Vulgaris and Streptococcus pyogenes, respectively. The findings confirmed that the Al2O3-NPs have small dimensions, high stability, and increased antibacterial activity.
